RARE \"Nobel Prize in Medicine\" Paul Nurse Hand Signed 4X6 Picture Postcard For Sale

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RARE \"Nobel Prize in Medicine\" Paul Nurse Hand Signed 4X6 Picture Postcard:
$69.99

Up for sale a RARE! "Nobel Prize in Medicine" Sir Paul Nurse Signed 4X6 Postcard of his painted portrait.

ES-6453

Sir

Paul Maxime 25

January 1949) is an English geneticist, former President of the Royal Society and

Chief Executive and Director of the Francis Crick Institute. He

was awarded the 2001 Nobel Prize in

Physiology or Medicine along with Leland Hartwell and Tim Hunt for their discoveries of protein molecules that

control the division of cells in the cell cycle. Nurse's mother went lived with relatives

while awaiting Paul's birth (at the age of 18) in order to hide illegitimacy. For the rest of their lives his maternal

grandmother pretended to be his mother and his mother pretended to be his

sister. Paul was brought up by his grandparents (whom he took to be his

parents) in North West London. He was educated at Lyon Park school in Alperton and Harrow County Grammar School.

He received his BSc degree in biology in 1970 from the University of Birmingham and his PhD degree in 1973

from the University of East Anglia for

research on Candida utilis. He then pursued

postdoctoral work at the University of Bern,

the University of Edinburgh and

the University of Sussex. Nurse

did not know that his "sister" was in fact his mother until he was in

his 50s: his application for a green card for US residency while president of Rockefeller University was,

to his surprise, rejected, despite his being a Nobel Prize winner, president of

a university and a knight; this was because he had submitted a short-form UK

birth certificate which did not name his parents. When he applied for a full

birth certificate he discovered the truth, to his astonishment. Nurse continued

his postdoctoral research at

the laboratory of Murdoch Mitchison at

the University of Edinburgh for

the next six years (1973–1979). Beginning in 1976, Nurse identified

the gene cdc2 in fission yeast (Schizosaccharomyces pombe).

This gene controls the progression of the cell cycle from G1 phase to S phase and the transition from G2 phase to mitosis. In 1987, Nurse identified the homologous gene in

human, Cdk1, which codes for a cyclin dependent kinase.

Working in fission yeast, Nurse identified the gene cdc2, which controls

the transition from G1 to S, when the cell grows in preparation for the

duplication of DNA, and G2 to M, when the cell divides. With his postdoc Melanie Lee, Nurse also found the corresponding gene, CDK1, in

humans. These genes stop and start cyclin dependent kinase (CDK) by adding or

removing phosphate groups.In 1984, Nurse joined the Imperial Cancer Research Fund (ICRF,

now Cancer Research UK). He

left in 1988 to chair the department of microbiology at the University of Oxford. He

then returned to the ICRF as Director of Research in 1993, and in 1996 was

named Director General of the ICRF, which became Cancer Research UK in 2002. In

2003, he became president of Rockefeller University in New York City where he continued work on the cell cycle

of fission yeast. In 2011 Nurse became the first Director and Chief Executive

of the UK Centre for Medical Research and

Innovation, now the Francis Crick Institute. On

30 November 2010, Nurse succeeded astrophysicist Martin Rees for a five-year term as President of the

Royal Society until 2015. Nurse has said good scientists must

have passion "to know the answer to the questions" that interest

them, along with good technical ability, and a set of attitudes including mental

honesty, self-criticism, open-mindedness and scepticism.

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